Concordia Pharmaceuticals: Developing Novel Cancer Therapeutics

Latest News

The Company is in Phase I/II clinical trials with Salirasib for pancreatic cancer at Johns Hopkins and has initiated a Phase II clinical trial for lung cancer at Memorial Sloan-Kettering Cancer Center.
[Released August 2007]

FDA grants Orphan-Drug designation for Salirasib for the treatment of pancreatic cancer.
[Released December 18, 2006]

Concordia has accepted the United States Adopted Names Council's (USAN) proposed name of salirasib as the USAN for FTS. A new stem, "rasib" was established to indicate the first RAS inhibitor.
[Released December 2006]

Salirasib: A Targeted Ras-Antagonist Therapy for Cancer

Click here to see a schematic Concordia has developed a new, first in class, orally effective, targeted Ras-antagonist therapy that acts to inhibit cancer by significantly impairing the disease's ability to replicate defective cells. We have obtained worldwide rights to a family of Ras-inhibitors and have selected Salirasib as our lead compound. Salirasib has been shown to inhibit the growth of Ras-driven cancer cells.

By exploiting the differences between cancer cells and normal cells, Salirasib can inhibit the growth of malignant cells without damaging healthy cells.

 More about Salirasib
 Salirasib Mechanism of Action