
The Company is in Phase I/II clinical trials with Salirasib for pancreatic
cancer at Johns Hopkins and has initiated a Phase II clinical trial for
lung cancer at Memorial Sloan-Kettering Cancer Center.
[Released August
2007]
FDA grants Orphan-Drug
designation for Salirasib for the treatment of pancreatic cancer.
[Released December 18, 2006]
Concordia has accepted the United States Adopted Names Council's (USAN)
proposed name of salirasib as the USAN for FTS. A new stem, "rasib" was
established to indicate the first RAS inhibitor.
[Released December 2006]
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Concordia has developed a new, first in class, orally effective, targeted
Ras-antagonist therapy that acts to inhibit cancer by significantly impairing
the disease's ability to replicate defective cells. We have obtained
worldwide rights to a family of Ras-inhibitors and have selected Salirasib
as our lead compound. Salirasib has been shown to inhibit the growth of
Ras-driven cancer cells.
By exploiting the differences between cancer cells and normal
cells, Salirasib can inhibit the growth of malignant cells without
damaging healthy cells.
More
about Salirasib
Salirasib
Mechanism of Action |